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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD2
All Species:
9.09
Human Site:
S478
Identified Species:
20
UniProt:
O14939
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14939
NP_002654.3
933
105987
S478
R
L
T
D
L
G
D
S
S
E
S
A
A
S
Q
Chimpanzee
Pan troglodytes
XP_511291
924
105027
S478
R
L
T
D
L
G
D
S
S
E
S
A
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001117754
892
101098
T455
P
C
P
D
S
P
A
T
P
D
L
S
H
N
Q
Dog
Lupus familis
XP_536610
854
96426
S439
F
I
T
D
W
W
L
S
P
E
I
Y
L
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P97813
933
106150
P478
R
L
T
D
L
G
D
P
S
E
P
V
H
L
Q
Rat
Rattus norvegicus
P70498
933
106019
P478
R
L
T
D
L
G
D
P
S
E
S
A
D
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422793
1072
123414
V498
R
L
T
D
V
G
S
V
K
R
M
G
A
V
K
Frog
Xenopus laevis
NP_001129642
1039
119219
V501
R
L
T
D
V
G
S
V
K
R
I
V
T
T
Q
Zebra Danio
Brachydanio rerio
XP_694649
927
106849
K471
L
S
D
L
D
S
P
K
Q
P
S
P
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194932
825
94056
I410
G
K
D
Y
Y
N
P
I
F
K
D
V
V
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
Y513
K
I
G
D
C
P
P
Y
I
W
P
G
K
D
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
92.1
77.2
N.A.
90
89.5
N.A.
N.A.
48.8
50.9
59.2
N.A.
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
97.2
93.7
80.7
N.A.
93.8
93.1
N.A.
N.A.
63.3
66.2
73.5
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
13.3
26.6
N.A.
66.6
86.6
N.A.
N.A.
40
40
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
40
40
N.A.
66.6
86.6
N.A.
N.A.
53.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
28
28
0
10
% A
% Cys:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
82
10
0
37
0
0
10
10
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
46
0
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
55
0
0
0
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% H
% Ile:
0
19
0
0
0
0
0
10
10
0
19
0
0
0
0
% I
% Lys:
10
10
0
0
0
0
0
10
19
10
0
0
10
10
10
% K
% Leu:
10
55
0
10
37
0
10
0
0
0
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
10
0
0
19
28
19
19
10
19
10
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
55
% Q
% Arg:
55
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% R
% Ser:
0
10
0
0
10
10
19
28
37
0
37
10
0
28
0
% S
% Thr:
0
0
64
0
0
0
0
10
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
19
0
0
19
0
0
0
28
10
10
0
% V
% Trp:
0
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
10
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _